At least twice a week, you should be soaking your retainer for 20 minutes. Just a heads up, though: ClearRetain Teeth Retainers, Mouth Guards, Night Guards Combine equal parts of water and vinegar in a bowl or dish. How to clean my retainer properly . If playback doesn't begin shortly, try restarting your device. Scrub with dish soap for 20 seconds, using a sponge or scrubber appropriate for the material of your retainer case. Pollan, most removable retainers shouldn't be so big that you have to sleep. Pat the case dry (don’t let it dry on the counter). First, you should clean it immediately after it’s removed from your mouth. Use a soft toothbrush or denture brush to. If your retainer isn't fitting properly, that can actually cause oral problems.according to dr. To clean the retainers properly, you mustn’t use toothpaste as it can damage the retainer, the only thing you have to do is water the aligner and the brush with warm water and brush it as yo...